Expression of aquaporin 1 and aquaporin 4 water channels in rat choroid plexus
نویسندگان
چکیده
منابع مشابه
Altered gravity downregulates aquaporin-1 protein expression in choroid plexus.
Aquaporin-1 (AQP1) is a water channel expressed abundantly at the apical pole of choroidal epithelial cells. The protein expression was quantified by immunocytochemistry and confocal microscopy in adult rats adapted to altered gravity. AQP1 expression was decreased by 64% at the apical pole of choroidal cells in rats dissected 5.5-8 h after a 14-day spaceflight. AQP1 was significantly overexpre...
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In order to gain insight into the molecular mechanisms that allow taste cells to respond to changes in their osmotic environment, we have used primarily immunocytochemical and molecular approaches to look for evidence of the presence of aquaporin-like water channels in taste cells. Labeling of isolated taste buds from the fungiform, foliate, and vallate papillae in rat tongue with antibodies ag...
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We investigated the expression of aquaporin (AQP) subtypes (AQP1-AQP9) in the rat pituitary gland by the reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry. Specific amplification by RT-PCR was observed in AQP1, AQP3, AQP4 and AQP5 but not in the others. AQP1 immunoreactivity was detected in the endothelial cells of blood vessels. No positive reaction to AQP3 was ...
متن کاملExpression of aquaporin-1 in the choroid plexus in communicating and non-communicating hydrocephalic rats
Departamento de Anatomía, Anatomía Patológica e Histología, Facultad de Medicina, Universidad de La Laguna, La Laguna, Tenerife, Islas Canarias, Spain, Departamento de Biotecnología, Instituto de Investigación y Ciencias de Puerto del Rosario, Puerto del Rosario, Fuerteventura, Islas Canarias, Spain and Departamento de Farmacología, Facultad de Medicina, Universidad de La Laguna, La Laguna, Ten...
متن کاملExpression of Aquaporin 1 and 4 in the Choroid Plexus and Brain Parenchyma of Kaolin-Induced Hydrocephalic Rats
Objective Aquaporin (AQP) is a recently discovered protein that regulates water homeostasis. The present study examines changes in AQP 1 and 4 in kaolin induced experimental hydrocephalic rats to elucidate the pathophysiology of water homeostasis in the disease. Methods Hydrocephalus was induced by percutaneous intracisternal injection of kaolin. The brain parenchyma and choroid plexus were o...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 2003
ISSN: 0005-2736
DOI: 10.1016/s0005-2736(02)00658-2